Book Hotels in Great Island, ME
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Top Great Island hotels
Cambria Hotel Portland Downtown-Old Port
25 HANCOCK STREET Portland ME
Fully refundableReserve now, pay when you stay
$293 nightly
The price is $325 total per night from Jul 26 to Jul 27
$325 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"We enjoyed our stay!!!! ;)"
Reviewed on Jul 21, 2026
Portland Regency Hotel & Spa
20 Milk Street Portland ME
$313 nightly
The price is $346 total per night from Jul 26 to Jul 27
$346 total
Jul 26 - Jul 27
Total with taxes and fees
A full-service spa, a hot tub, and a restaurant are all featured at this smoke-free hotel. Unwind with a drink at one of the 2 bars/lounges and enjoy freebies ...
"The property was in a perfect locations and offered a gym and spa along with places to eat. The staff was very helpful and the food was delicious! My sisters and I enjoyed our stay."
Reviewed on Jul 21, 2026
Holiday Inn Portland-By the Bay by IHG
88 Spring St Portland ME
Fully refundable
$225 nightly
The price is $249 total per night from Aug 17 to Aug 18
$249 total
Aug 17 - Aug 18
Total with taxes and fees
This hotel features a restaurant, an indoor pool, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"The rooms are a bit dated and look like they could use some minor repairs (ie: caulking in the bathroom). The a/c required nudging to get it to stay cool. The door in my room didn't close well and I had to slam it to get it to shut all the way. The staff was very nice and the location was perfect. ..."
Reviewed on Jul 21, 2026
La Quinta Inn & Suites by Wyndham Portland DT/Maine Med
340 Park Ave Portland ME
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $198 total per night from Jul 26 to Jul 27
$198 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport ...
"always a great stay here"
Reviewed on Jul 21, 2026
Comfort Inn South Portland Airport
90 Maine Mall Rd South Portland ME
Fully refundableReserve now, pay when you stay
$153 nightly
The price is $167 total per night from Aug 16 to Aug 17
$167 total
Aug 16 - Aug 17
Total with taxes and fees
This hotel doesn't skimp on freebies - guests receive free buffet breakfast, free WiFi, and a free airport shuttle. Traveling on business? Take advantage of ...
"Great place to stay"
Reviewed on Jul 21, 2026
Fireside Inn & Suites Portland
81 Riverside St Portland ME
Fully refundableReserve now, pay when you stay
$151 nightly
The price is $167 total per night from Jul 26 to Jul 27
$167 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the seasonal ...
"The price is fair and clean"
Reviewed on Jul 21, 2026
Clarion Hotel Portland Airport ME
1230 Congress St Portland ME
Fully refundable
$144 nightly
The price is $159 total per night from Aug 2 to Aug 3
$159 total
Aug 2 - Aug 3
Total with taxes and fees
This hotel features an indoor pool and a gym. Traveling on business? Take advantage of the business center, free WiFi in public areas, and free airport shuttle. ...
"Clean room. Pleasant staff, willing to suggest local businesses."
Reviewed on Jul 21, 2026
Clarion Pointe South Portland
675 Main Street I-95 South Portland ME
Fully refundable
$94 nightly
The price is $102 total per night from Aug 20 to Aug 21
$102 total
Aug 20 - Aug 21
Total with taxes and fees
This hotel features a restaurant, an outdoor pool, and a bar/lounge. Traveling on business? Take advantage of the business center and WiFi in public areas. Enjoy ...
"Only problem we had was that the TV in our room wasn't working. We asked for someone to come to check it out but no one did. So we did not watch any tv for our stay. Also they really didn't come to clean our room. The room was comfortable, the AC was great the bed was very comfortable. It was a good ..."
Reviewed on Jul 21, 2026
Portland Harbor Hotel
468 Fore Street Portland ME
Fully refundableReserve now, pay when you stay
$421 nightly
The price is $465 total per night from Jul 26 to Jul 27
$465 total
Jul 26 - Jul 27
Total with taxes and fees
This hotel features 3 coffee shops/cafes and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public areas, ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Hotels in Great Island with star-rating
Check Great Island Hotels by Star Rating
4 Star Hotels
13 properties
Recent Great Island hotel reviews by fellow wanderers
Portland Regency Hotel & Spa
5 out of 5
Posted 1 hour ago
Travelocity Verified Review
"The property was in a perfect locations and offered a gym and spa along with places to eat. The staff was very helpful and the food was delicious! My sisters and I enjoyed our stay."
A verified traveler stayed at Portland Regency Hotel & Spa
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